Peripheral Artery Disease (PAD) is a condition in which the arteries that take oxygenated blood to the lower limbs become clogged with plaque and cholesterol and prevent the tissue in the lower limbs from receiving adequate amounts of blood. The symptoms of PAD typically begin with mild leg pain after walking, but as the condition worsens, the feet can become cold from lack of circulation and develop sores that do not heal. In the most extreme cases gangrene can set in and require amputation.

Although many people with PAD experience no symptoms, it is important to watch for early signs. If someone has PAD, they are also very likely to have arterial clogging elsewhere in the body, especially around the heart area, which can lead to heart attacks.